Pancreatic Expression Database

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Datasets in the Pancreatic Expression Database

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A set of highly relevant published pancreatic cancer papers was manually processed, data checked and results loaded into a relational database.

The data was annotated and integrated with the available Ensembl human genome annotations including gene related annotations, sequences, SNPs, gene structure, multi-species and antibody data from the human protein atlas.

We will be updating the database on a regular basis with new findings in the pancreatic cancer field. We also welcome and support pancreatic cancer scientists worldwide to deposit and share their data. If you have data that you would like to submit or any other enquiry, please email help@pancreasexpression.org.uk

Article	Journal	Title	Date	Volume	Issue
Adachi J et al	Genome Biology	The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins.	Sep-06	7	9
Anderson NL et al	Mol Cell Proteomics	The human plasma proteome: a nonredundant list developed by combination of four separate sources	Apr-04	3	4
Arumugam T et al	Cancer Research	Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer	July 15,2009	69	14
Badea L et al	Hepato-Gastroenterology	Combined Gene Expression Analysis of Whole-Tissue and Microdissected Pancreatic Ductal Adenocarcinoma identifies Genes Specifically Overexpressed in Tumor Epithelia	2008	88	0
Bloomston M	JAMA	MicroRNA Expression Patterns to Differentiate Pancreatic Adenocarcinoma From Normal Pancreas and Chronic Pancreatitis	May-07	297	17
Buchloz M et al	Oncogene	Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions.	Oct-05	24	44
Capurso G et al	Endocrine-Related Cancer	Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets	Jun-06	13	2
Chen R et al	Gastroenterology	Pancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escape	Oct-05	129	4
Chen R et al	Molecular and Cellular Proteomics	Quantitative proteomics analysis reveals that proteins differentially expressed in chronic pancreatitis are also frequently involved in pancreatic cancer	Aug-07	6	8
Chen R et al	Pancreas	Comparison of Pancreas Juice Proteins from Cancer Versus Pancreatitis Using Quantitative Proteomic Analysis	Jan-07	34	1
Chen R et al	Proteomics	Quantitative proteomic profiling of pancreatic cancer juice	May-06	6	13
Crnogorac-Jurcevic T et al	Gastroenterology	Proteomic Analysis of Chronic Pancreatitis and Pancreatic Adenocarcinoma	Nov-05	129	5
Crnogorac-Jurcevic T et al	J Pathology	Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalent	Jul-03	201	1
Crnogorac-Jurcevic T et al	Oncogene	Expression profiling of microdissected pancreatic adenocarcinomas	Jul-02	21	29
Crnogorac-Jurcevic T et al	Oncogene	Gene expression profiles of pancreatic cancer and stromal desmoplasia	Nov-01	20	50
Esposito I et al	Neoplasia	Tumor-Suppressor Function of SPARC-Like Protein 1/Hevin in Pancreatic Cancer	Jan-07	9	1
Friess H et al	Cell Mol Life Sci	Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer.	Jun-03	60	6
Fukushima N et al	Modern Pathology	Gene expression alterations in the non-neoplastic parenchyma adjacent to infiltrating pancreatic ductal adenocarcinoma	Jun-05	18	6
Fukushima N et al	Oncogene	Characterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarrays	Dec-04	23	56
Gnjatic S et al	PNAS	Seromic profiling of ovarian and pancreatic cancer	Mar-10	107	11
Gronborg M et al	Journal of Proteome Research	Comprehensive Proteomic Analysis of Human Pancreatic Juice	Sep-04	3	5
Grutzmann R et al	Neoplasia	Gene Expression Profiling of Microdissected Pancreatic Ductal Carcinomas Using High-Density DNA Microarrays	Sep-04	6	5
Hu L et al	Electrophoresis	Two-dimensional protein database of human pancreas	Feb-04	25	3
Iacobuzio-Donahue CA et al	Am J Pathol	Discovery of novel tumor markers of pancreatic cancer using global gene expression technology.	Apr-02	160	4
Jimeno A et al	Cancer Research	Coordinated Epidermal Growth Factor Receptor Pathway Gene Overexpression Predicts Epidermal Growth Factor Receptor Inhibitor Sensitivity in Pancreatic Cancer	2008	68	8
Jones S et al	Science	Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses	Sep-08	321	5897
Kakisaka T et al	Journal of Chromatography B	Plasma proteomics of pancreatic cancer patients by multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis (2D-DIGE): Up-regulation of leucine-rich alpha-2-glycoprotein in pancreatic cancer	Jun-07	852	1
Lee EJ et al	International Journal of Cancer	Expression profiling identifies microRNA signature in pancreatic cancer	Dec-06	120	5
Li J et al	Molecular Cancer	Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer	Apr-05	4	1
Logsdon CD et al	Cancer Research	Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer.	May-03	63	10
Lu Z et al	Proteomics	Differential expression profiling of human pancreatic adenocarcinoma and healthy pancreatic tissue	Dec-04	4	12
Maitra A et al	Clinical Cancer Research	Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays	Dec-03	9	0
Mees ST et al	Journal of Surgical Research	Analyzing miRNAs in Ductal Adenocarcinomas of the Pancreas	inpress	0	0
Nakamura T et al	Cancer Research	Zonal Heterogeneity for Gene Expression in Human Pancreatic Carcinoma	Aug-07	67	16
Nakamura T et al	Oncogene	Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection	Mar-04	23	13
Pei H et al	Cancer Cell	FKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt	2009	16	1
Pilarsky C et al	Journal of Cellularand Molecular Medicine	Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling.	Dec-08	12	6
Pogue-Geile KL et al	Plos Medicine	Palladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer Mechanism	Dec-06	3	12
Prasad NB et al	Cancer Research	Gene Expression Profiles in Pancreatic Intraepithelial Neoplasia Reflect the Effects of Hedgehog Signaling on Pancreatic Ductal Epithelial Cells	Mar-05	65	5
Roldo C et al	Journal of Clinical Oncology	MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior	Oct-06	24	29
Sato A et al	Am J Pathol	Gene Expression Profiling Identifies Genes Associated with Invasive Intraductal Papillary Mucinous Neoplasms of the Pancreas	Mar-04	164	3
Segara D et al	Clin Cancer Res	Expression of HOXB2, a Retinoic Acid Signaling Target in Pancreatic Cancer and Pancreatic Intraepithelial Neoplasia	May-05	11	9
Selga E et al	Genome Medicine	Networking of differentially expressed genes in human cancer cells resistant to methotrexate	2009	1	9
Shen J et al	Cancer Research	Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.	Dec-04	64	24
Song D et al	Molecular Cancer Therapeutics	Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer	Mar-10	9	3
Szafranska et al	Oncogene	MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma	2007	26	0
Tan ZJ et al	World J Gastroenterol	Analysis of gene expression profile of pancreatic carcinoma using cDNA microarray	Apr-03	9	4
Terris B et al	Am J Pathol	Characterization of Gene Expression Profiles in Intraductal Papillary-Mucinous Tumors of the Pancreas	May-02	160	5
Van Heek NT et al	Cancer Biol Ther	Gene Expression Profiling Identifies markers of ampullary adenocarcinoma	Jul-04	3	7
Wang Y et al	J Clin Invest	CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells	2009	119	6
Weeks M et al	PROTEOMICS - Clinical Applications	Analysis of the urine proteome in patients with pancreatic ductal adenocarcinoma	Jul-08	2	7
Yu KH et al	Journal of Proteome Research	Characterization of Proteins in Human Pancreatic Cancer Serum Using Differential Gel Electrophoresis and Tandem Mass Spectrometry	Sep-05	4	5
Zhang H et al	Clinical Proteomics	Profiling the potential biomarkers for cell differentiation of pancreatic cancer using iTRAQ and 2-D LC-MS/MS	Jul-09	3	7
Zhang L et al	Gastroenterology	Salivary Transcriptomic Biomarkers for Detection of Resectable Pancreatic Cancer	2010	138	3
Zhang Y et al	World Journal of Surgery	Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis	Apr-09	33	4
Copy Number Variations
Harada T et al	oncogenomics	Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays	2008	27	0
Jones S et al	Science	Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses	Sep-08	321	5897
Lin L et al	Oncology	Integrated analysis of copy number alterations and loss of heterozygosity in human pancreatic cancer using a high-resolution, single nucleotide polymorphism array.	2008	75	0
Suzuki A et al	Cancer Science	Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization	May-08	99	5