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Datasets in the Pancreatic Expression Database

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A set of highly relevant published pancreatic cancer papers was manually processed, data checked and results loaded into a relational database.

The data was annotated and integrated with the available Ensembl human genome annotations including gene related annotations, sequences, SNPs, gene structure, multi-species and antibody data from the human protein atlas.

We will be updating the database on a regular basis with new findings in the pancreatic cancer field. We also welcome and support pancreatic cancer scientists worldwide to deposit and share their data. If you have data that you would like to submit or any other enquiry, please email help@pancreasexpression.org.uk

Article Journal Title Date Volume Issue
Adachi J et alGenome BiologyThe human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins.Sep-0679
Anderson NL et alMol Cell ProteomicsThe human plasma proteome: a nonredundant list developed by combination of four separate sourcesApr-0434
Arumugam T et alCancer ResearchEpithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic CancerJuly 15,20096914
Badea L et alHepato-GastroenterologyCombined Gene Expression Analysis of Whole-Tissue and Microdissected Pancreatic Ductal Adenocarcinoma identifies Genes Specifically Overexpressed in Tumor Epithelia2008880
Bloomston MJAMAMicroRNA Expression Patterns to Differentiate Pancreatic Adenocarcinoma From Normal Pancreas and Chronic PancreatitisMay-0729717
Buchloz M et alOncogeneTranscriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions.Oct-052444
Capurso G et alEndocrine-Related CancerGene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targetsJun-06132
Chen R et alGastroenterologyPancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escapeOct-051294
Chen R et alMolecular and Cellular ProteomicsQuantitative proteomics analysis reveals that proteins differentially expressed in chronic pancreatitis are also frequently involved in pancreatic cancerAug-0768
Chen R et alPancreasComparison of Pancreas Juice Proteins from Cancer Versus Pancreatitis Using Quantitative Proteomic AnalysisJan-07341
Chen R et alProteomicsQuantitative proteomic profiling of pancreatic cancer juiceMay-06613
Crnogorac-Jurcevic T et alGastroenterologyProteomic Analysis of Chronic Pancreatitis and Pancreatic AdenocarcinomaNov-051295
Crnogorac-Jurcevic T et alJ PathologyMolecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalentJul-032011
Crnogorac-Jurcevic T et alOncogeneExpression profiling of microdissected pancreatic adenocarcinomasJul-022129
Crnogorac-Jurcevic T et alOncogeneGene expression profiles of pancreatic cancer and stromal desmoplasiaNov-012050
Esposito I et alNeoplasiaTumor-Suppressor Function of SPARC-Like Protein 1/Hevin in Pancreatic CancerJan-0791
Friess H et alCell Mol Life SciMicroarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer.Jun-03606
Fukushima N et alModern PathologyGene expression alterations in the non-neoplastic parenchyma adjacent to infiltrating pancreatic ductal adenocarcinomaJun-05186
Fukushima N et alOncogeneCharacterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarraysDec-042356
Gnjatic S et alPNASSeromic profiling of ovarian and pancreatic cancerMar-1010711
Gronborg M et alJournal of Proteome ResearchComprehensive Proteomic Analysis of Human Pancreatic JuiceSep-0435
Grutzmann R et alNeoplasiaGene Expression Profiling of Microdissected Pancreatic Ductal Carcinomas Using High-Density DNA MicroarraysSep-0465
Hu L et alElectrophoresisTwo-dimensional protein database of human pancreasFeb-04253
Iacobuzio-Donahue CA et alAm J PatholDiscovery of novel tumor markers of pancreatic cancer using global gene expression technology.Apr-021604
Jimeno A et alCancer ResearchCoordinated Epidermal Growth Factor Receptor Pathway Gene Overexpression Predicts Epidermal Growth Factor Receptor Inhibitor Sensitivity in Pancreatic Cancer2008688
Jones S et alScienceCore Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses Sep-083215897
Kakisaka T et alJournal of Chromatography BPlasma proteomics of pancreatic cancer patients by multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis (2D-DIGE): Up-regulation of leucine-rich alpha-2-glycoprotein in pancreatic cancerJun-078521
Lee EJ et alInternational Journal of CancerExpression profiling identifies microRNA signature in pancreatic cancerDec-061205
Li J et alMolecular CancerEnhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancerApr-0541
Logsdon CD et alCancer ResearchMolecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer.May-036310
Lu Z et alProteomicsDifferential expression profiling of human pancreatic adenocarcinoma and healthy pancreatic tissueDec-04412
Maitra A et alClinical Cancer ResearchGlobal expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarraysDec-0390
Mees ST et alJournal of Surgical ResearchAnalyzing miRNAs in Ductal Adenocarcinomas of the Pancreasinpress00
Nakamura T et alCancer ResearchZonal Heterogeneity for Gene Expression in Human Pancreatic CarcinomaAug-076716
Nakamura T et alOncogeneGenome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissectionMar-042313
Pei H et alCancer CellFKBP51 Affects Cancer Cell Response to Chemotherapy by Negatively Regulating Akt2009161
Pilarsky C et alJournal of Cellularand Molecular MedicineActivation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling.Dec-08126
Pogue-Geile KL et alPlos MedicinePalladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer MechanismDec-06312
Prasad NB et alCancer ResearchGene Expression Profiles in Pancreatic Intraepithelial Neoplasia Reflect the Effects of Hedgehog Signaling on Pancreatic Ductal Epithelial CellsMar-05655
Roldo C et alJournal of Clinical OncologyMicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical BehaviorOct-062429
Sato A et alAm J PatholGene Expression Profiling Identifies Genes Associated with Invasive Intraductal Papillary Mucinous Neoplasms of the PancreasMar-041643
Segara D et alClin Cancer ResExpression of HOXB2, a Retinoic Acid Signaling Target in Pancreatic Cancer and Pancreatic Intraepithelial NeoplasiaMay-05119
Selga E et alGenome MedicineNetworking of differentially expressed genes in human cancer cells resistant to methotrexate 200919
Shen J et alCancer ResearchProtein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.Dec-046424
Song D et alMolecular Cancer Therapeutics Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancerMar-1093
Szafranska et alOncogeneMicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma2007260
Tan ZJ et alWorld J GastroenterolAnalysis of gene expression profile of pancreatic carcinoma using cDNA microarrayApr-0394
Terris B et alAm J PatholCharacterization of Gene Expression Profiles in Intraductal Papillary-Mucinous Tumors of the PancreasMay-021605
Van Heek NT et alCancer Biol TherGene Expression Profiling Identifies markers of ampullary adenocarcinomaJul-0437
Wang Y et alJ Clin InvestCEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells20091196
Weeks M et alPROTEOMICS - Clinical ApplicationsAnalysis of the urine proteome in patients with pancreatic ductal adenocarcinomaJul-0827
Yu KH et alJournal of Proteome ResearchCharacterization of Proteins in Human Pancreatic Cancer Serum Using Differential Gel Electrophoresis and Tandem Mass SpectrometrySep-0545
Zhang H et alClinical ProteomicsProfiling the potential biomarkers for cell differentiation of pancreatic cancer using iTRAQ and 2-D LC-MS/MSJul-0937
Zhang L et alGastroenterologySalivary Transcriptomic Biomarkers for Detection of Resectable Pancreatic Cancer20101383
Zhang Y et alWorld Journal of SurgeryProfiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR AnalysisApr-09334
Copy Number Variations
Harada T et aloncogenomicsGenome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays2008270
Jones S et alScienceCore Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses Sep-083215897
Lin L et alOncologyIntegrated analysis of copy number alterations and loss of heterozygosity in human pancreatic cancer using a high-resolution, single nucleotide polymorphism array.2008750
Suzuki A et alCancer ScienceIdentification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridizationMay-08995